Emerging therapeutic approaches

Title: Emerging therapeutic approaches
Creator: McLean, Gary; Girkin, Jason; Solari, Roberto
Relation: Rhinovirus Infections: Rethinking the Impact on Human Health and Disease p. 239-263
Publisher Link: http://dx.doi.org/10.1016/B978-0-12-816417-4.00009-3
Publisher: Elsevier
Resource Type: book chapter
Date: 2019
Description: There are currently no approved drugs for the treatment of rhinovirus (RV) or indeed of any picornavirus infection, despite decades of drug discovery efforts. Likewise there are no licensed vaccines for RV even though trials began in the late 1960s. However, a large number of experimental approaches that target RV itself, the RV-induced inflammatory response, or promote broad RV-specific immunity have been through preclinical development and clinical trials with mixed success. This chapter will amalgamate these studies and highlight the most promising and applicable therapeutic approaches.
Subject: rhinovirus; therapies; chemotherapeutics; viral targets; host targets; vaccines
Identifier: http://hdl.handle.net/1959.13/1452358
Identifier: uon:44421
Identifier: ISBN:9780128164181
Language: eng